Infections & Post-Infectious Conditions
- Tick-borne infections (Lyme disease and co-infections)
- Long COVID and post-viral syndromes
- Chronic infections and immune dysregulation
- Mold toxicity and biotoxin-related illness
Complex Chronic Illness & Cancer Supportive Care in Bellevue
Specialized medical care for complex and persistent health conditions, including integrative cancer support.
Over 30 Years of Experience in the Diagnosis and Treatment of Complex Conditions, Including Tick-Borne Infections, Long COVID, Mast Cell Activation Syndrome (MCAS), Mold Toxicity, and Autoimmune Conditions.
Your Partner in Chronic Illness & Cancer Support
For patients navigating persistent or complex health concerns, Holistique Medical Center provides expert medical integrative care and comprehensive supportive cancer care. Our approach emphasizes close provider–patient relationships, accessibility, and long-term wellness. For patients with active cancer or a history of cancer, our supportive cancer care takes a whole-person approach, addressing physical, emotional, and systemic needs.
Our team specializes in complex and persistent conditions, focusing on identifying root causes in priority order and building personalized, integrative care plans that support you throughout your journey. Holistique serves as a partner in care for patients seeking deeper answers, coordinated support, and a thoughtful path forward through chronic illness and cancer support.
Complex & Chronic Conditions
Complex & Chronic Conditions: From Lyme to Long COVID
Immune, Inflammatory & Mast Cell Disorders
- Mast Cell Activation Syndrome (MCAS)
- Histamine intolerance
- Autoimmune conditions
- Chronic inflammation
Gastrointestinal & Microbiome Dysfunction
- Chronic gastrointestinal dysfunction, including IBS
- Gut microbiome imbalance and dysbiosis
- Digestive inflammation, malabsorption, and food sensitivities
Hormonal, Metabolic & Mitochondrial Conditions
- Hormonal and endocrine imbalance (including adrenal, thyroid, and metabolic dysfunction)
- Mitochondrial dysfunction
- Chronic fatigue-related conditions
Neurological & Cognitive Conditions
- Brain fog and cognitive impairment
- Neuroinflammation
- Autonomic nervous system dysfunction (dysautonomia, POTS)
Environmental & Toxin-Related Illness
- Chemical sensitivities and detoxification support
- Heavy metal and plastic toxicity
- Environmental illness and exposure syndromes
Integrative Cancer Supportive Care
We provide personalized supportive care for individuals undergoing or recovering from cancer treatment, working alongside your oncology team to support overall health, resilience, and quality of life.
Support may include:
- Immune system support during and after treatment
- Nutritional and metabolic optimization
- Symptom management and quality-of-life support
Learn more:
Supportive Cancer CareSupportive oncology care is provided in coordination with your primary oncology team and does not replace conventional cancer treatment.
Approach
Our Approach: Integrative Care for Chronic Illness & Cancer Support
Step 1: Comprehensive Evaluation
We start with a thorough evaluation using both conventional and advanced testing to uncover the root contributors to your health challenges.
- Functional & conventional lab testing (immune, hormones, gut, cellular function)
- Targeted screening for chronic infections, toxins, immune issues, or cancer-related markers
- RGCC analysis for select complex or cancer-related cases
- Full review of your medical history, treatments, symptoms, and goals
Step 2: Individualized Care Plan
Based on your results, we build a truly personalized care plan focused on restoring balance and supporting every aspect of your well-being.
- Integrative therapies and medical treatments as needed
- Nutrition, IV, and lifestyle support
- Ongoing review and adjustment as your needs evolve
Step 3: Whole-Person Support
We treat more than symptoms. Our care is grounded in science, compassion, and partnership, supporting you physically, emotionally, and throughout your recovery.
For those living with, recovering from, or with a history of cancer, we provide whole-person, personalized support. Our care addresses mind, body, and well-being to help you restore resilience and quality of life.
Integrative Cancer Supportive Care
We support cancer patients with personalized care addressing the mind, body, and soul.
At Holistique, Integrative Cancer Supportive Care means treating the whole person, not just the disease. Our focus is on supporting your body, mind, and spirit at every stage, whether you are currently in treatment, recovering, have a history of cancer, or want to reduce future risk.
What We Do:
- Personalized Support
- Whole-Person Approach
- Complementing Conventional Treatment
- Long-Term Wellness
- Prevention-Focused: We address root contributors, optimize the body’s defenses, and focus on prevention, helping you reduce the risk of recurrence and safeguard your long-term health.
With over 30 years of experience in supportive cancer care, our team brings expertise, compassion, and advanced integrative therapies to help you achieve the best possible outcome and long-term well-being.
Dr. Darvish earned a Fellowship in Adjunctive Cancer Therapies in 2010.
Read Dr. Darvish’s latest article, Specific Oligonucleotide Therapy (SOT) or Q-REstrain in Long COVID: A Precision-Based Integrative Approach
Technology
Integrative Medical Therapies in Chronic Illness & Cancer Supportive Care
Explore physician-guided integrative therapies used to support complex chronic illness, immune dysfunction, and cancer supportive care.
Q-Restrain / SOT (Specific Oligonucleotide Therapy)
Personalized gene-targeted therapy used as supportive care alongside conventional treatment for chronic infections.
- Chronic viral & bacterial infections
- Cancer-support care (non-oncology)
- Cellular repair pathways
- Immune modulation & difficult-case management
Administered by certified RGCC-trained Holistique providers.
Ozone Therapy (10 Pass, MAH, & more)
Ozone therapy introduces medical-grade ozone to support oxygenation, circulation, and immune modulation.
- Enhances oxygen utilization and mitochondrial function
- Supports detoxification and microbial balance
- Used for chronic infections, Lyme, and inflammatory conditions
- Administered via IV, injection, or insufflation
Peptide Therapy
Peptides are short chains of amino acids that act as signaling molecules, influencing a wide range of biological processes.
- Supports tissue repair, metabolism, and immune function
- Used for anti-aging, fat loss, and performance optimization
- May enhance sleep, cognition, and recovery
- Targeted action with minimal systemic side effects
Mistletoe Therapy
Prescription botanical injection therapy used in European integrative medicine to support immune function and cancer-supportive care.
- Immune system activation and modulation
- Supportive cancer care (non-oncology)
- Reduction of inflammation and treatment-related side effects
- Support for chronic infections and immune dysregulation
Prescription therapy administered under medical supervision by Holistique providers.
IV Vitamin C Therapy
High-dose intravenous vitamin C therapy used to support immune modulation, cellular repair, and oxidative balance.
- Immune system support
- Antioxidant and pro-oxidant cellular effects (dose-dependent)
- Supportive cancer care and chronic infections
- Reduction of inflammation and fatigue
Dosage and protocols individualized based on clinical evaluation.
Methylene Blue Therapy
Prescription metabolic and antimicrobial therapy used to support mitochondrial function and complex infections.
- Antimicrobial support for chronic infections
- Mitochondrial energy support
- Neurological and cognitive support
- Used in conjunction with IV or laser therapies
Administered orally or intravenously with medical oversight.
Weber Intravenous Laser Therapy
Delivers targeted light wavelengths (red, blue, green, yellow, infrared, UV) into the bloodstream.
- Activates immune response
- Reduces inflammation and pain
- Regenerates tissue
Hyperbaric Oxygen Therapy (HBOT)
Delivers 100% oxygen in a pressurized chamber to increase tissue oxygenation.
- Enhances wound healing and reduces inflammation
- Supports recovery from brain injuries and stroke
- Used in chronic infections and post-surgical healing
- Improves oxygen delivery to oxygen-starved tissues
IV Nutrient & Mitochondrial Support
Customized infusions that deliver essential raw materials for cellular repair.
- Vitamins & minerals
- Amino acids & antioxidants
- NAD+, Mitochondrial cofactors, Glutathione & Peptides
- Supports healing, detox, immune function, and vitality
LDA / LDI Immunotherapy
Low-dose immune desensitization therapy designed to regulate abnormal immune responses to allergens and pathogens.
- Immune system recalibration
- Support for chronic infections and allergies
- Mast cell and histamine regulation
- Reduction of immune overreaction
Administered using specialized protocols under medical supervision.
Ondamed Biofeedback Therapy
Frequency-based biofeedback therapy using pulsed electromagnetic and sound frequencies to support nervous system regulation, immune balance, and overall physiological coherence.
- Supports hormonal and nervous system balance
- Assists the body in reducing inflammation and pain
- Used as supportive therapy for chronic illness, neurological, digestive, and immune-related conditions
- Often incorporated into integrative care plans to improve tolerance to other therapies
Emotional Clearing
Integrative therapeutic approaches designed to address emotional and psychological contributors to chronic illness and healing.
- Identification and release of emotional blockages
- Support for nervous system regulation
- Complementary care for chronic illness and cancer support
- Mind-body integration
Utilized as part of a comprehensive integrative care plan.
Musculoskeletal & Structural Therapies
Therapies focused on restoring structural alignment, nervous system regulation, and functional movement to support pain relief, recovery, and whole-body balance.
- Spinal Manipulation
- Sacral-Occipital Technique (SOT)
- Neuro-Cranial Restructuring (NCR)
- Craniosacral Therapy
- Visceral Manipulation
- Pelvic Floor Therapy
- Myofunctional Therapy (Face, Tongue & Jaw)
- Vagus Nerve Evaluation & Rehabilitation
Acupuncture & Related Modalities
Restore balance, support healing, and relieve pain with evidence-based therapies designed to address the complex needs of chronic illness and regenerative medicine patients.
- Acupuncture
- Cupping Therapy
- Cold Laser Therapy (Low-Level Laser Therapy)
- Reflexology
Massage & Lymphatic Therapies
Alleviate tension, enhance circulation, and promote detoxification with advanced massage and lymphatic techniques tailored for chronic illness recovery and regenerative care.
- Sports Massage
- Swedish Massage
- Deep Tissue Massage
- Relaxation Massage
- Lymphatic Drainage Massage
- Ionic Foot Bath
Low Dose Naltrexone (LDN) Therapy
Low-dose immunomodulatory therapy used to support immune regulation and chronic inflammatory conditions.
- Immune system modulation
- Support for autoimmune and inflammatory conditions
- Pain and symptom regulation
- Supportive therapy in complex chronic illness
Next Steps in Your Care
If you’re exploring care for complex chronic illness or supportive care during cancer treatment or recovery, our team is here to help guide you.
Request Appointment or reach our care team, call or text (425) 451-0404
Announcements
What's New at Holistique
Best in the PNW, Three Years Running
The Seattle Times has named Holistique a Best in the PNW award recipient for 2026, in both Best Naturopathy and Best Alternative Therapies. It is the third consecutive year we have been recognized in both categories. Thank you to our patients and our community for voting for us.
See Our Awards
EMSCULPT NEO®
EMSCULPT NEO is an FDA-cleared medical device used to strengthen muscle, improve mobility, and reduce the appearance of localized fat. At Holistique, this technology is integrated into personalized care plans for patients seeking regenerative, hormone, or functional support…
Discover EMSCULPT NEO®
Therapeutic Plasma Exchange (TPE)
Therapeutic Plasma Exchange is an advanced medical procedure that removes and replaces plasma to help reduce inflammatory proteins and immune complexes circulating in the blood. At Holistique, TPE is provided by Circulate Health and integrated into personalized care plans supporting longevity, immune balance, and complex chronic conditions.
Discover TPEHolistique Home Wellness Collection
Physician-curated supplements, advanced diagnostic kits, and home-care tools designed by Dr. Darvish to elevate cellular health, enhance detoxification, and strengthen long-term vitality.
Shop Collection
Gut Zoomer Microbiome Test
Khosh Ultra Biotic Lean Probiotic
Vibrant Wellness Diagnostic Panels
Khosh Collagen Plus Supplement
LightStim LED Light Therapy Device
Khosh S-Acetyl Glutathione
Latest Articles
Holistique Health Insights
Hormone Metabolic Health
HRT Not Working? How Senescent Cells and TPE Explain Ongoing Symptoms
You started hormone therapy expecting to feel like yourself again. Your labs may even look good now. But the fatigue, brain fog, or joint pain never fully lifted. If this sounds familiar, the missing piece may not be your hormone levels at all. It may be cellular senescence.
Detoxification
Why Detoxification Is the Missing Piece in Hormone Balance
When women come to see me struggling with perimenopause, the conversation almost always starts with hormones. But after three decades of practice, I have learned that hormone therapy alone is rarely the whole story. If detoxification pathways are overwhelmed, even well-dosed bioidentical hormones are fighting an uphill battle.
Regenerative Medicine
Natural Senolytics: Can Food-Derived Compounds Like EGCG and Curcumin Clear Senescent Cells?
Senolytics are compounds that selectively clear senescent cells, the aged, inflammatory cells that drive much of what we call aging. A growing body of research points to natural compounds, including fisetin, quercetin, EGCG, and curcumin, as having real senolytic activity.
