Women-Specific Hormonal Symptoms
- Hot flashes or night sweats
- Menstrual cycle changes or irregular periods
- Premenstrual symptoms (PMS)
- Vaginal dryness or discomfort
- Urinary changes or incontinence
Hormone Therapy & Metabolic Health
Restore balance, energy, and metabolic health with precision-tailored hormone therapy and personalized metabolic care for menopause, perimenopause, and low testosterone.
Over 30 years of proven clinical experience providing personalized bio-identical hormone therapy (BHRT) for men and women.
Hormone & Metabolic Health for Men & Women
Hormones influence multiple systems in the body, including metabolism, energy, mood, cognition, sleep, sexual health, and overall physical and emotional well-being. With over 30 years of clinical experience, our physicians are experts in diagnosing, supporting and optimizing hormone balance. This includes support for perimenopause, menopause, post menopause and andropause (low testosterone).
Our metabolic health care considers hormonal balance alongside a multidisciplinary approach designed to support healthy body composition, strengthen muscle mass, and reduce excess body fat over time.
Our goal is to help you feel like yourself again, with renewed energy, clarity, and confidence.
Hormone Health
Common Symptoms of Hormonal Imbalance
Energy & Cognitive Function
- Persistent fatigue/Chronic Fatigue
- Brain fog or difficulty concentrating
- Low motivation or reduced mental clarity
- Headaches and migraines
- Memory issues
Mood & Emotional Health
- Anxiety or irritability
- Low mood or depressive symptoms
- Emotional changes
- Sleep issues/Insomnia
Metabolic & Body Composition
- Weight gain or difficulty losing weight
- Unexplained Weight Loss
- Sarcopenia (progressive loss of muscle mass and strength associated with aging)
- Blood sugar dysregulation
Sexual Health & Vitality
- Reduced libido
- Sexual dysfunction
- Decreased overall vitality
Physical & Structural Health
- Joint pain, arthritis, or muscle discomfort
- Changes in skin elasticity, sagging skin, or skin quality
- Hair loss
- Reduced physical resilience
- Numbness and tingling
Hormonal, Metabolic & Mitochondrial Conditions
- Hormonal and endocrine imbalance (including adrenal, thyroid, and metabolic dysfunction)
- Mitochondrial dysfunction
- High cholesterol/High blood pressure
Approach
Our Clinical Approach to Hormone Therapy and Metabolic Health
Step 1: Individualized Evaluation and Testing
Hormonal and metabolic health are highly individual. At Holistique Medical Center, care begins with a comprehensive clinical evaluation rather than a one-size-fits-all protocol. Each patient's medical history, symptoms, and current concerns are carefully reviewed alongside appropriate laboratory testing, which may include comprehensive urine, blood, and saliva testing, to better understand hormone levels, their metabolites, methylation, metabolic function, and related health indicators.
Hormones We Evaluate and Optimize:
- Estrogen (including estrone, estradiol and estriol and their metabolites)
- Progesterone
- Testosterone
- Dehydroepiandrosterone (DHEA)
- Pregnenolone
- Thyroid, adrenal, and growth hormones
- Insulin and related metabolic markers
Evaluation is individualized and guided by symptoms, life stage, and overall health goals.
Step 2: Personalized Hormone Dosing and Delivery Methods
Hormone therapy is tailored to the individual, with dosing and delivery methods selected based on clinical findings, symptoms, lifestyle factors, and life stage. Hormones are prescribed and compounded specifically for each patient and may be delivered in capsule, cream, or pellet form, depending on clinical appropriateness and patient preference.
When pellet therapy is indicated, we utilize EvexiPEL®, a state-of-the-art, clinically advanced method of bioidentical hormone replacement therapy (BHRT) designed for consistent dosing over time. This personalized approach allows care to be adjusted thoughtfully and precisely rather than following standardized dosage.
Care is individualized and may include integrative, non-hormone approaches and/or prescription-based therapies. Optimizing hormonal balance without prescription hormones may incorporate peptides, targeted supplementation, lifestyle and dietary guidance, and other supportive medical therapies.
Step 3: Continuous Monitoring & Personalized Care
Hormone levels fluctuate and individual needs change over time, so ongoing testing and follow-up allow therapy to be adjusted depending on laboratory findings, clinical response, and overall health markers over time. Dosage may be refined as needed to maintain appropriate therapeutic balance and safety. Our clinicians provide ongoing guidance at each step of care.
Step 4: Integrated Metabolic and Weight Support
Hormonal balance and metabolic health are closely connected. For patients with concerns related to weight or metabolic health, treatment plans may include integrated metabolic and weight support alongside hormone and lifestyle therapy. This may involve targeted strategies to support metabolic function, insulin sensitivity, body composition, and overall health.
When clinically appropriate, care may incorporate peptide-based therapies such as Compounded GLP-1 medications, prescribed in personalized dosing and usually combined with supportive nutrients such as B-vitamins to support metabolism and detoxification pathways. These therapies are considered as part of a broader, individualized plan that may also include nutrition, lifestyle guidance, and supportive therapies (EMSCULPT NEO, BallancerPro lymphatic compression therapy, IV Therapy) based on each patient's needs and goals.
Weight Management & Metabolic Health
We support patients with personalized weight management, metabolic care and detoxification focused on improving body composition, metabolic function, and long-term health.
At Holistique Medical Center, weight management goes beyond calories or short-term weight loss. Our approach centers on understanding the root contributors to weight resistance, including hormones, metabolism, insulin sensitivity, detoxification pathways, and lifestyle factors.
What We Offer:
- Personalized body composition optimization
- Root-cause evaluation of weight and metabolic concerns
- Integrated hormone and metabolic support
- Peptide-based therapies, including compounded GLP-1 medications when clinically appropriate
- Nutrition, lifestyle, and movement guidance
- Supportive therapies (EMSCULPT NEO, BallancerPro lymphatic compression therapy, IV Nutrient Therapy and more) to enhance metabolic and detox pathways
- Ongoing clinical oversight and health coaching
Our physicians create individualized care plans that may include hormone balancing, metabolic support, peptide therapies such as Compounded GLP-1 medication, and personalized nutrition and lifestyle strategies. Care is designed to support metabolic health, muscle-to-fat balance, and sustainable results, with a focus on long-term well-being rather than quick fixes.
Announcements
What's New at Holistique
Flexible Financing with Cherry
Holistique has partnered with Cherry to offer flexible monthly payment plans, so you can get the care you need today and pay over time. Explore plans and check your eligibility.
Explore Financing
EMSCULPT NEO®
EMSCULPT NEO is an FDA-cleared medical device used to strengthen muscle, improve mobility, and reduce the appearance of localized fat. At Holistique, this technology is integrated into personalized care plans for patients seeking regenerative, hormone, or functional support…
Discover EMSCULPT NEO®
Therapeutic Plasma Exchange (TPE)
Therapeutic Plasma Exchange is an advanced medical procedure that removes and replaces plasma to help reduce inflammatory proteins and immune complexes circulating in the blood. At Holistique, TPE is integrated into personalized care plans supporting longevity, immune balance, and complex chronic conditions.
Discover TPEIntegrative Medical Therapies for Hormone & Metabolic Health
Explore physician-guided integrative therapies designed to support hormonal balance, metabolic function, and weight-related health concerns through individualized medical care.
Hormone Optimization
EMSCULPT NEO®
Electromagnetic therapy that sculpts and strengthens muscle while improving the appearance of fat and body composition.
- Builds and strengthens muscle in targeted treatment areas
- Supports non-invasive fat reduction in treated areas
- Improves muscle tone and firmness
- Helps counter age- and hormone-related muscle loss (sarcopenia)
- Enhances strength, mobility, and functional performance
Clinically guided treatment using FDA-cleared technology.
EMSELLA®
Non-invasive electromagnetic therapy that strengthens pelvic floor muscles to support bladder control and core stability.
- High-intensity focused electromagnetic stimulation of pelvic floor muscles
- Strengthens muscles involved in bladder support and continence
- Supports neuromuscular control and pelvic stability
- Addresses pelvic floor weakening associated with aging, hormonal shifts, and weight changes
- Used as adjunctive therapy within hormone and metabolic health programs
Clinically guided treatment using FDA-cleared technology.
Compounded Bio-Identical Hormone Therapy
Custom-compounded bio-identical hormones prescribed to match individual clinical needs.
- Plant-derived hormones structurally identical to those produced by the body
- Customized formulations based on testing, symptoms, and life stage
- Adjusted for dosage, combination, and delivery method
- Prescribed and monitored under medical supervision
- Compounded specifically for each patient through licensed compounding pharmacies
Hormone Pellet Therapy (Evexipel®)
Long-acting bio-identical hormone delivery designed to provide consistent dosing over time.
- Testosterone, estrogen, and other bio-identical hormones
- Supports stable hormone levels between visits
- Option for patients who prefer less frequent dosing
- Prescribed and monitored under medical supervision
- Utilizes Evexipel® pellets administered using the Evexia Method for precision dosing and consistent delivery
Injectable Hormone & Peptide Therapy
Prescription injectable therapies used to support hormonal and metabolic balance.
- Hormone injections when clinically appropriate
- Peptide therapies for metabolic and physiologic support
- Personalized dosing based on testing and clinical response
- Integrated into broader hormone or metabolic health plans
- Administered under physician oversight
Regenerative Injection Therapies (PRP-Based)
Autologous regenerative therapies using platelet-rich plasma to support tissue repair and healing.
- Supports tissue repair and healing responses
- Uses growth factors concentrated from the patient's blood
- May be used in musculoskeletal or sexual health care
- Integrated with other medical or regenerative therapies
- Offered as adjunctive care when clinically appropriate
Ozone-Supported Injection Therapy/10 Pass
Adjunctive medical injection therapy incorporating ozone to support circulation and tissue oxygenation.
- Used to support circulation and tissue oxygenation
- May be combined with other injectable therapies
- Selected based on individual clinical needs
- Part of integrative treatment planning
- Applied selectively under medical supervision
P-Shot® (PRP Therapy for Men)
Platelet-rich plasma (PRP) therapy derived from the patient's own blood to support male sexual health.
- Supports male sexual health and function
- Uses concentrated growth factors from PRP
- May be combined with supportive therapies
- Performed as part of individualized care planning
- Offered when clinically appropriate
V-Shot® (PRP Therapy for Women)
PRP-based therapy designed to support female pelvic and sexual health.
- May support concerns related to pelvic health
- Uses platelet-rich plasma from the patient's own blood
- Considered for urinary or sexual wellness concerns when clinically appropriate
- May be paired with EMSELLA® or other supportive therapies
- Performed under medical supervision
Metabolic Health
EMSCULPT NEO®
Non-invasive body contouring and muscle stimulation therapy used to support strength development and body composition goals.
- Uses synchronized radiofrequency and high-intensity electromagnetic energy to stimulate muscle contractions
- Supports muscle strengthening and improved muscle tone
- May assist with reducing localized fat in treated areas
- Incorporated as a supportive therapy alongside medical metabolic health care
GLP-1 Peptide Therapy
Prescription-based peptide therapy used to support metabolic regulation and body composition when clinically appropriate.
- Compounded GLP-1 Medication
- Supports appetite regulation and insulin signaling
- May be combined with supportive nutrients such as B-vitamins
- Personalized dosing based on clinical evaluation
- Prescribed and monitored by a physician
Hormonal Balancing
Medical evaluation and optimization of key hormones that influence metabolism, energy, and body composition.
- Assessment of insulin resistance and blood sugar regulation
- Thyroid hormone evaluation
- Adrenal hormone assessment
- Testosterone and estrogen optimization for men and women
- Integrated hormone support, especially for patients over 40
Nutritional Medicine
Personalized nutrition strategies designed to support metabolic health, body composition, and long-term wellness.
- Comprehensive evaluation of dietary patterns and metabolic needs
- Personalized nutrition strategies aligned with body composition goals
- Support for muscle maintenance and healthy fat reduction
- Integrated with hormone, peptide, and lifestyle-based programs
Lymphatic Drainage Therapy
Therapies focused on supporting lymphatic circulation and elimination pathways during body composition changes.
- Manual lymphatic drainage massage
- BallancerPro lymphatic compression therapy
- Supports toxin clearance as fat is mobilized
- Reduces metabolic congestion
- Used as adjunctive therapy within metabolic health programs
Body Composition Ozone Therapy
Localized ozone-based injections used as supportive care for circulation and tissue oxygenation.
- Localized ozone injections (e.g., abdomen, thighs, jowls)
- Supports tissue oxygenation and circulation
- Used selectively based on clinical evaluation
- Integrated with metabolic health programs
Nutrient IV Therapy
Intravenous nutrient support designed to enhance energy production, detoxification pathways, immune function, and cellular health.
- Evaluation of nutrient deficiencies through clinical testing
- Customized IV infusions tailored to individual needs
- Supports energy, immune function, and cellular regeneration
- IV delivery bypasses the gut for direct cellular access
- Higher-dose delivery than oral absorption allows
IV nutrient therapy, ozone therapy, and NAD+ IV therapy may be prescribed when clinically indicated.
Ondamed Biofeedback and Acupuncture Therapy
Frequency-based biofeedback therapy using pulsed electromagnetic and sound frequencies and acupuncture to support nervous system regulation, immune balance, and overall physiological coherence.
- Supports hormonal and nervous system balance
- Assists the body in reducing inflammation and pain
- Used as supportive therapy for chronic illness, neurological, digestive, and immune-related conditions
- Often incorporated into integrative care plans to improve tolerance to other therapies
Health Coaching
Clinical coaching support designed to reinforce behavior change and support long-term success.
- Ongoing coaching support tailored to individual needs
- Guidance on nutrition, movement, and daily habits
- Support for emotional and behavioral factors impacting weight concerns
- Collaboration with physicians and the broader care team
Next Steps in Your Care
Contact us to get started with hormone optimization or metabolic health care. Our care team is here to help guide you.
Request Appointment or reach our care team, call or text (425) 451-0404
Holistique Home Wellness Collection
Physician-curated supplements, advanced diagnostic kits, and home-care tools designed by Dr. Darvish to elevate cellular health, enhance detoxification, and strengthen long-term vitality.
Shop Collection
Gut Zoomer Microbiome Test
Khosh Ultra Biotic Lean Probiotic
Vibrant Wellness Diagnostic Panels
Khosh Collagen Plus Supplement
LightStim LED Light Therapy Device
Khosh S-Acetyl Glutathione
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