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EvexiPEL Hormone Pellet Therapy in Bellevue

A bioidentical hormone pellet therapy designed to restore hormonal balance without the peaks and valleys of pills, creams, or injections. Precision dosing based on your labs and symptoms delivers a steady, long-lasting stream of hormones.

Our team has been performing pellet insertion procedures since 2008, bringing years of specialized experience to every treatment.

A gloved hand holding a single EvexiPEL bioidentical hormone pellet, about the size of a grain of rice, at Holistique Medical Center in Bellevue

What It Is

What Is EvexiPEL?

EvexiPEL pellets are tiny, custom-compounded cylinders, about the size of a grain of rice, made from plant-derived bioidentical hormones that share the same molecular structure as those your body naturally produces. Pellets typically contain estradiol, testosterone, or both, precisely dosed based on comprehensive lab testing and your individual symptoms.

Once inserted just beneath the skin in a quick in-office procedure, the pellets release a steady, consistent dose of hormones directly into the bloodstream for roughly three to four months, even responding to your body's natural rhythm during exercise or stress, rather than delivering a flat, fixed dose around the clock.

Bioidentical & precisely dosed

Plant-derived hormones, structurally identical to your own, compounded to a dose calculated from your labs and symptoms.

Steady, continuous release

Placed just beneath the skin in a quick in-office procedure, then releasing hormones consistently for roughly three to four months.

Responds to your body

Pellets can respond to your body's natural rhythm during exercise or stress, rather than delivering a flat, fixed dose around the clock.

The Difference

Why EvexiPEL vs. Other Pellet Therapies?

Not all hormone pellets are the same. Here's what sets EvexiPEL apart from generic or compounded alternatives:

Data-driven dosing

Rather than a one-size-fits-all approach, EvexiPEL uses a proprietary algorithm that factors in dozens of data points from your labs, symptoms, and health history to calculate your dose, replacing guesswork with precision.

Pharmacy quality standards

EvexiPEL pellets are compounded exclusively through FDA-registered, PCAB-accredited pharmacies, which is not guaranteed with all generic pellet suppliers.

Specialized insertion training

Providers who offer EvexiPEL complete dedicated training in a gentle, standardized insertion technique. Generic pellet therapy often varies widely by provider experience and training.

Atraumatic insertion technique

Our naturopathic physicians use an atraumatic insertion method designed to minimize tissue trauma, resulting in less bruising and fewer complications than the insertion techniques used at many other clinics.

Consistency you can rely on

The combination of precision dosing, pharmacy standards, and technique is designed to minimize the inconsistent results and complications that can come with less standardized pellet programs.

Benefits

Why Choose Pellet Therapy?

Consistent levels

Avoids the daily highs and lows common with pills, creams, and patches.

Convenience

No daily regimen to remember, inserted once every few months.

Personalized dosing

Based on your specific labs, symptoms, and health goals.

Quick procedure

Typically 15–30 minutes, done right in the office.

The Process

The Process

  1. Consultation

    We review your medical history, symptoms, and wellness goals.

  2. Hormone testing

    Blood work confirms your current hormone levels and guides your personalized dose.

  3. Insertion

    Our pellet insertion procedure is performed by our highly experienced naturopathic physicians. The insertion site (typically the hip or upper buttock) is numbed with local anesthetic, a small incision is made, and the pellets are placed just beneath the skin.

  4. Follow-up

    You and your provider will monitor your symptoms and labs to fine-tune future dosing.

Pellet Therapy

Pellet Insertion Procedure

Pellet Pre-Insertion Procedure

Pellet Post-Insertion Procedure

Prepare

Before Your Appointment

  • Complete any required lab work and health intake forms in advance.
  • Eat a light meal before your visit.
  • Wear loose-fitting clothing that allows easy access to the hip/buttock area.
  • Arrange for a ride if you'd like, though most clients are able to drive themselves home.

Aftercare

Post-Pellet Care Instructions

  • Keep the area dry: Avoid showering directly over the insertion site, swimming, or soaking in a bath for 48–72 hours.
  • Limit activity: Avoid strenuous exercise, heavy lifting, and activities that strain the insertion area for 5–7 days to reduce the risk of pellet extrusion.
  • Ice as needed: Apply an ice pack in short intervals during the first 24 hours to reduce swelling.
  • Watch for normal healing signs: Mild bruising, tenderness, or redness at the site is common for 3–4 days.
  • Keep the dressing on: Leave the bandage in place as directed, typically for the first day or two.
  • Avoid tight clothing: Loose pants or clothing over the insertion site help prevent irritation.

Contact us if you experience: Significant swelling, spreading redness, fever, drainage, a pellet visibly working its way out of the skin (extrusion), or pain that worsens instead of improving. These can be signs of infection or complication and should be evaluated promptly.

FAQ

Frequently Asked Questions

  • How long do the pellets last?

    Most patients experience steady hormone release for approximately three to four months before a repeat insertion is needed.

  • When will I notice results?

    Many clients report symptom relief within 2–4 weeks, though full hormone optimization can take up to several months, especially after your first insertion.

  • Does the insertion hurt?

    The site is numbed with local anesthetic beforehand, so most patients report little to no pain during the procedure itself. Mild soreness for a few days afterward is normal.

  • Can I adjust my dose once the pellets are inserted?

    No. Unlike pills or patches, pellet dosing cannot be changed once inserted. This is why thorough lab work and a detailed consultation beforehand are so important to getting your dose right.

  • Is EvexiPEL only for women?

    No. EvexiPEL is designed for both men and women experiencing symptoms of hormone imbalance or decline, with dosing tailored to each.

  • What symptoms might EvexiPEL help with?

    Common reasons clients pursue hormone pellet therapy include fatigue, brain fog, low libido, mood changes, and symptoms related to perimenopause or menopause. Your provider will help determine whether pellet therapy fits your specific symptoms and labs.

  • Are there risks?

    As with any procedure, there are risks, including bruising, infection, or rare pellet extrusion. Serious complications are uncommon when performed by a trained provider using sterile technique, but it's important to follow aftercare instructions closely and report any concerning symptoms.

EvexiPEL is a prescription hormone therapy administered under naturopathic physician guidance following a full consultation and lab review. It is not appropriate for everyone; your provider will evaluate your medical history to determine if pellet therapy is right for you.

Ready to restore your balance?

Schedule your EvexiPEL consultation and we'll review your history, symptoms, and labs to determine whether hormone pellet therapy is right for you.

Schedule Your EvexiPEL Consultation or reach our care team, call or text (425) 451-0404

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